TAL1 — TAL bHLH transcription factor 1, erythroid differentiation factor
TAL1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TAL1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Hematopoietic progenitor cells | Erythroid Progenitor Program Erythropoietic | ABCC5, CTNNBL1, MINPP1, NBAS, PDCD4, PDZD8, RNF130, SLC40A1 +3 more |
About the gene
| Synonyms | bHLHa17, SCL, TCL5 |
|---|---|
| Chromosome | 1: 47216290-47232225 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors |
| Molecular function | Developmental protein, DNA-binding |
| Biological process | Differentiation, Transcription, Transcription regulation |
Function
Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of erythroid differentiation (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.