TBC1D1 — TBC1 domain family member 1
TBC1D1 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TBC1D1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Endothelial Junction Identity Endothelial cell development | ADGRF5, AKAP13, CDH5, CXCL12, DENND5A, FGF12, FURIN, HSPA12B +13 more | View in SCUBA |
| Neutrophils | Stress Kinase Signaling Stress | ANKRD44, APBB1IP, HIPK3, IGF1R, MAP3K5, MEF2A, NEK7, PARP8 +2 more |
About the gene
| Synonyms | KIAA1108, TBC, TBC1 |
|---|---|
| Chromosome | 4: 37891084-38139175 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Transporters |
| Molecular function | GTPase activation |
Function
May act as a GTPase-activating protein for Rab family protein(s). May play a role in the cell cycle and differentiation of various tissues. Involved in the trafficking and translocation of GLUT4-containing vesicles and insulin-stimulated glucose uptake into cells (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.