TEP1 — Telomerase associated protein 1
TEP1 belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TEP1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | Cytoskeletal Remodeling Cytoskeletal | A1CF, ANK3, BMP3, CCNYL1, DISP2, DOCK4, ECE1, ENPP1 +18 more | View in SCUBA |
About the gene
| Synonyms | p240, TLP1, TP1, TROVE1, VAULT2 |
|---|---|
| Chromosome | 14: 20365667-20413501 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins |
| Molecular function | Ribonucleoprotein, RNA-binding |
Function
Component of the telomerase ribonucleoprotein complex that is essential for the replication of chromosome termini. Also a component of the ribonucleoprotein vaults particle, a multi- subunit structure involved in nucleo-cytoplasmic transport (By similarity). Responsible for the localizing and stabilizing vault RNA (vRNA) association in the vault ribonucleoprotein particle. Binds to TERC (By similarity).
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.