ECE1 — Endothelin converting enzyme 1
ECE1 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ECE1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | ER-Golgi Trafficking Protein processing & ER | ATL3, DIAPH2, EID1, GOLIM4, KTN1, MAGT1, PGK1, SHISA5 +4 more | View in SCUBA |
| Enterocytes | KLF4 Terminal Differentiation Epithelial development | KLF4, MARCHF3, MDK, RASSF6, SHROOM3, SIK3, TRANK1, TRIM38 | View in SCUBA |
| Fibroblasts | Basement Membrane ECM ECM production | BSG, COL6A1, COL6A2, COMT, ECM1, FNDC3B, LAMB1, LAMC1 +2 more | View in SCUBA |
| Neutrophils | TLR2 Innate Signaling Innate immunity | AATK, CHST15, CYRIA, DHX34, ERGIC1, MAP4K4, MKNK1, STK40 +4 more |
About the gene
| Synonyms | ECE |
|---|---|
| Chromosome | 1: 21217247-21345572 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins |
| Molecular function | Hydrolase, Metalloprotease, Protease |
Function
Converts big endothelin-1 to endothelin-1
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.