SCUBA

TMOD2 — Tropomodulin 2

TMOD2 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

TMOD2's module in each cell type

Cell typeModuleShares the module with
Lymphatic endothelialEndothelial Receptor Signaling
endothelial development
ADGRF5, ART4, ENTREP1, FLRT2, P3H2, PDGFC, PLSCR4, SNCAIP +2 moreView in SCUBA

About the gene

SynonymsNTMOD
Chromosome15: 51751597-51816363
Predicted locationIntracellular
Essential geneNo
Protein classPredicted intracellular proteins
Molecular functionActin-binding

Function

Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton (By similarity)

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.