TTL — Tubulin tyrosine ligase
TTL belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TTL's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Immune Cell Contamination Cell contamination | ANKRD65, CADM1, CD79B, CLEC1A, IL3RA, JDP2, KAZN, MYH11 +2 more | View in SCUBA |
About the gene
| Synonyms | MGC46235 |
|---|---|
| Chromosome | 2: 112482156-112541739 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Predicted intracellular proteins |
| Molecular function | Ligase |
Function
Catalyzes the post-translational addition of a tyrosine to the C-terminal end of detyrosinated alpha-tubulin
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.