MYH11 — Myosin heavy chain 11
MYH11 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
MYH11's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Immune Cell Contamination Cell contamination | ANKRD65, CADM1, CD79B, CLEC1A, IL3RA, JDP2, KAZN, MYLK +2 more | View in SCUBA |
| Fibroblasts | Smooth Muscle Identity Cytoskeletal | ACTG2, ALDH1B1, C3orf70, CNN1, FBXL22, HSD17B6, JPH2, KCNH2 +12 more | View in SCUBA |
| Pericytes | Smooth Muscle Contractile Cytoskeletal | GPRC5C, NET1, NRGN, PALLD, PLN, RERGL, SYNE1, SYNM +2 more | View in SCUBA |
| Smooth muscle cells | SMC Contractile Apparatus Contractility | ACTG2, CFL2, CKB, CSRP1, FLNA, ILK, LMOD1, PPP1R12B +3 more | View in SCUBA |
About the gene
| Synonyms | SMHC, SMMHC, SMMS-1 |
|---|---|
| Chromosome | 16: 15703135-15857028 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins |
| Molecular function | Actin-binding, Calmodulin-binding, Motor protein, Muscle protein, Myosin |
Function
Muscle contraction
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.