KAZN — Kazrin, periplakin interacting protein
KAZN belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
KAZN's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Immune Cell Contamination Cell contamination | ANKRD65, CADM1, CD79B, CLEC1A, IL3RA, JDP2, MYH11, MYLK +2 more | View in SCUBA |
| Enterocytes | Mature enterocyte transport Absorption | ABCG8, ANO6, ANXA13, PIK3C2G, RASGEF1B, SLC16A10, TCEA3, TLN2 +1 more | View in SCUBA |
| Fibroblasts | CCL11 Secretory Fibroblast ECM production | ANK3, ARHGAP24, CCL11, COL16A1, COL18A1, DTX4, F11R, GABRA2 +5 more | View in SCUBA |
| Smooth muscle cells | Capillary Pericyte Development | ADAP2, ADRA2A, ANKRD29, CCL8, CNGA1, ENPEP, EPHA2, EPS8L1 +10 more | View in SCUBA |
About the gene
| Synonyms | C1orf196, FLJ43806, KAZRIN, KIAA1026 |
|---|---|
| Chromosome | 1: 13892792-15118043 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Biological process | Keratinization |
Function
Component of the cornified envelope of keratinocytes. May be involved in the interplay between adherens junctions and desmosomes. The function in the nucleus is not known
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.