SCUBA

UBAP2 — Ubiquitin associated protein 2

UBAP2 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

UBAP2's module in each cell type

Cell typeModuleShares the module with
MacrophagesRNA Processing Transport
Housekeeping
BCL2, CDYL, CPSF6, DHX15, DHX9, EFR3A, EXOC1, FBXO38 +18 moreView in SCUBA

About the gene

SynonymsbA176F3.5, FLJ22435, KIAA1491
Chromosome9: 33921693-34049388
Predicted locationIntracellular
Essential geneNo
Protein classDisease related genes, Predicted intracellular proteins

Function

Recruits the ubiquitination machinery to RNA polymerase II for polyubiquitination, removal and degradation, when the transcription-coupled nucleotide excision repair (TC-NER) machinery fails to resolve DNA damage. May promote the degradation of ANXA2.

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.