UNC119B — Unc-119 lipid binding chaperone B
UNC119B belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
UNC119B's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Angiogenic Endothelial Identity Endothelial cell development | ADAMTSL2, ARHGAP29, COL13A1, CTNNB1, EDIL3, EML1, ETS1, EXOC3L1 +14 more | View in SCUBA |
About the gene
| Synonyms | MGC5139, POC7B |
|---|---|
| Chromosome | 12: 120710458-120723640 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Biological process | Cilium biogenesis/degradation, Protein transport, Transport |
Function
Myristoyl-binding protein that acts as a cargo adapter: specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. Binds myristoylated NPHP3 and plays a key role in localization of NPHP3 to the primary cilium membrane. Does not bind all myristoylated proteins. Probably plays a role in trafficking proteins in photoreceptor cells
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.