EML1 — EMAP like 1
EML1 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
EML1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Angiogenic Endothelial Identity Endothelial cell development | ADAMTSL2, ARHGAP29, COL13A1, CTNNB1, EDIL3, ETS1, EXOC3L1, FHOD1 +14 more | View in SCUBA |
| Smooth muscle cells | Matrix-integrin interaction ECM remodeling | C1S, FBN1, ITGA1, ITGAV, LRP1, P4HA2, VMP1 | View in SCUBA |
About the gene
| Synonyms | ELP79, EMAP, EMAPL, HuEMAP |
|---|---|
| Chromosome | 14: 99737693-99942060 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Predicted intracellular proteins |
Function
Modulates the assembly and organization of the microtubule cytoskeleton, and probably plays a role in regulating the orientation of the mitotic spindle and the orientation of the plane of cell division. Required for normal proliferation of neuronal progenitor cells in the developing brain and for normal brain development. Does not affect neuron migration per se
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.