VARS1 — Valyl-tRNA synthetase 1
VARS1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
VARS1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Chromatin TF Regulation DNA/chromatin regulation | ALDH9A1, ARMC1, ATIC, ERAP2, HDAC7, KAT8, LTN1, PHF14 +10 more |
About the gene
| Synonyms | VARS, VARS2 |
|---|---|
| Chromosome | 6: 31777518-31795752 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins |
| Molecular function | Aminoacyl-tRNA synthetase, Ligase |
| Biological process | Protein biosynthesis |
Function
Catalyzes the attachment of valine to tRNA(Val)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.