VSTM1 — V-set and transmembrane domain containing 1
VSTM1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
VSTM1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Monocytes | BPI Antibacterial Response Antibacterial | ADGRG3, ANXA3, BPI, CMTM2, CST7, CYP4F3, LGALS12, MGAM +6 more | View in SCUBA |
About the gene
| Synonyms | UNQ3033 |
|---|---|
| Chromosome | 19: 54040825-54063953 |
| Predicted location | Intracellular, Membrane, Secreted |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins |
| Molecular function | Cytokine |
| Biological process | Immunity |
Function
Behaves as a cytokine, promoting IL17A secretion by CD4+ T-cells, and differentiation and activation of IL17 producing helper T-cells (TH17). Inhibitory immune receptor involved in the regulation of phagocytes
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.