ANXA3 — Annexin A3
ANXA3 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ANXA3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Inflammatory ECM Remodeling ECM remodeling | ABI3BP, ADRA2C, CGNL1, CLIC3, ELN, FBLN2, FGF18, GUCY1A1 +5 more | View in SCUBA |
| Monocytes | BPI Antibacterial Response Antibacterial | ADGRG3, BPI, CMTM2, CST7, CYP4F3, LGALS12, MGAM, RGL4 +6 more | View in SCUBA |
| Neutrophils | Pentose Phosphate Pathway Housekeeping | ARPC2, CAP1, CDA, GYG1, HMGB2, LBR, PGD, SNX3 +1 more |
About the gene
| Synonyms | ANX3 |
|---|---|
| Chromosome | 4: 78551747-78610451 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins |
| Molecular function | Phospholipase A2 inhibitor |
Function
Inhibitor of phospholipase A2, also possesses anti-coagulant properties. Also cleaves the cyclic bond of inositol 1,2-cyclic phosphate to form inositol 1-phosphate
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.