ZG16B — Zymogen granule protein 16B
ZG16B belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ZG16B's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | Epithelial Innate Immunity Inflammation | ADAM9, AGPAT4, ALOX5, ANXA1, ARFGAP3, ASPH, AZGP1, BACE2 +32 more | View in SCUBA |
About the gene
| Synonyms | HRPE773, JCLN2, PRO1567 |
|---|---|
| Chromosome | 16: 2830253-2839585 |
| Predicted location | Secreted |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted secreted proteins |
Function
Plays an important role in pancreatic tumor progression and metastasis. Promotes pancreatic cancer cells migration and invasion through the TLR4/MyD88/NF-kaapaB signaling pathway, without the involvement of the TLR4/TRIF pathway.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.