ANKS1B — Ankyrin repeat and sterile alpha motif domain containing 1B
ANKS1B belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ANKS1B's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | T cell activation TCR/AP1/NFKb pathway | ARF6, CCT6A, EHD4, HNRNPM, IRF4, MAP2K3, PFDN2, TRIB1 +3 more | View in SCUBA |
About the gene
| Synonyms | AIDA-1, ANKS2, cajalin-2, EB-1 |
|---|---|
| Chromosome | 12: 98726457-99984936 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
Isoform 2 may participate in the regulation of nucleoplasmic coilin protein interactions in neuronal and transformed cells. Isoform 3 can regulate global protein synthesis by altering nucleolar numbers. Isoform 4 may play a role as a modulator of APP processing. Overexpression can down-regulate APP processing
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.