CLC — Charcot-Leyden crystal galectin
CLC belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CLC's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Hematopoietic progenitor cells | Eosinophil Differentiation Granulocyte development | DTWD2, EPX, ERN1, EXD3, IL5RA, MS4A3, PRG2 |
About the gene
| Synonyms | Gal-10, LGALS10, MGC149659 |
|---|---|
| Chromosome | 19: 39731255-39738029 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
Regulates immune responses through the recognition of cell- surface glycans. Essential for the anergy and suppressive function of CD25-positive regulatory T-cells (Treg)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.