SCUBA

EXD3 — Exonuclease 3'-5' domain containing 3

EXD3 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

EXD3's module in each cell type

Cell typeModuleShares the module with
Hematopoietic progenitor cellsEosinophil Differentiation
Granulocyte development
CLC, DTWD2, EPX, ERN1, IL5RA, MS4A3, PRG2

About the gene

SynonymsFLJ20433, LOC54932, mut-7, Nbr
Chromosome9: 137306896-137423211
Predicted locationIntracellular
Essential geneNo
Protein classPredicted intracellular proteins
Molecular functionExonuclease, Hydrolase, Nuclease

Function

Possesses 3'-5' exoribonuclease activity. Required for 3'-end trimming of AGO1-bound miRNAs (By similarity)

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.