CLDN12 — Claudin 12
CLDN12 belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CLDN12's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | Inflamed Barrier Remodeling Inflammation | ABHD2, AKIRIN2, CAPN8, CD55, EPB41L2, INPP1, ITGA6, ME1 +17 more | View in SCUBA |
About the gene
| Chromosome | 7: 90383721-90513402 |
|---|---|
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Predicted membrane proteins |
Function
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.