INPP1 — Inositol polyphosphate-1-phosphatase
INPP1 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
INPP1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | NF-kB feedback TCR/AP1/NFKb pathway | ADTRP, AKAP5, CDIP1, CDKN2A, CLEC7A, MAP3K5, N4BP1, PBXIP1 +8 more | View in SCUBA |
| Endothelial | Endothelial Quiescence Endothelial cell development | CCRL2, CDC42EP3, CGAS, CHSY1, CYTH1, HES5, HIPK3, ID1 +7 more | View in SCUBA |
| Innate lymphoid cells | RNA Chromatin Regulation RNA processing & translation | ACADM, AURKAIP1, BUD23, CBX3, CMC2, COPB1, DNAJA2, DYNC1LI1 +19 more | View in SCUBA |
About the gene
| Chromosome | 2: 190343570-190371665 |
|---|---|
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Predicted intracellular proteins |
| Molecular function | Hydrolase |
Function
Mg(2+)-dependent phosphatase that catalyzes the hydrolysis of the 1-position phosphate from inositol 1,4-bisphosphate and inositol 1,3,4-trisphosphate and participates in inositol phosphate metabolism
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.