DZIP3 — DAZ interacting zinc finger protein 3
DZIP3 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
DZIP3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Natural Killer cells | Mature NK Identity Differentiation | ABCB1, ADAM28, ADGRG3, CCDC141, CD160, CMTM7, IKZF3, LZTFL1 +5 more | View in SCUBA |
About the gene
| Synonyms | hRUL138, PPP1R66 |
|---|---|
| Chromosome | 3: 108589705-108694840 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins |
| Molecular function | RNA-binding, Transferase |
| Biological process | Ubl conjugation pathway |
Function
E3 Ubiquitin ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Able to specifically bind RNA
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.