EAF1 — ELL associated factor 1
EAF1 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
EAF1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Macrophages | NF-κB Inflammatory Activation Inflammatory | ADM, CCL2, CCL20, CCL7, CLEC4E, CXCL1, CXCL2, CXCL3 +19 more | View in SCUBA |
| Monocytes | Inflammatory Metabolic Reprogramming Inflammatory | ACTN1, ADAM8, DGAT2, GPAT3, MCTP2, PTPN7, SLC25A37, SLC2A3 | View in SCUBA |
About the gene
| Chromosome | 3: 15427598-15450635 |
|---|---|
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | Activator |
| Biological process | Transcription, Transcription regulation |
Function
Acts as a transcriptional transactivator of ELL and ELL2 elongation activities.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.