EI24 — EI24 autophagy associated transmembrane protein
EI24 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
EI24's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Smooth muscle cells | Membrane Protein Turnover Housekeeping | ATP6AP2, AXL, BSG, CAP1, CBX6, MFAP4, SSR2, TCEAL9 +1 more | View in SCUBA |
About the gene
| Synonyms | EPG4, PIG8, TP53I8 |
|---|---|
| Chromosome | 11: 125569280-125584684 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Cancer-related genes, Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters |
| Biological process | Apoptosis, Autophagy |
Function
Acts as a negative growth regulator via p53-mediated apoptosis pathway. Regulates formation of degradative autolysosomes during autophagy (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.