SCUBA

SSR2 — Signal sequence receptor subunit 2

SSR2 belongs to a gene co-expression module in 10 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

SSR2's module in each cell type

Cell typeModuleShares the module with
CD19⁺ B cellsB cell activation signaling
B cell maturation
ANKRD44, BLK, BTN3A2, EVI2B, GAPT, GPSM3, LBH, LTB +9 moreView in SCUBA
CD4⁺ T cellsLeukocyte adhesion signaling
migration & adhesion
ARHGDIB, BIN1, CD37, DGKA, DGKZ, EIF3F, EIF3L, EIF4B +22 moreView in SCUBA
EndothelialHousekeeping Metabolic
Housekeeping
ANXA5, ATP5MC3, CCT5, COX6B1, CTSL, DCTPP1, ERH, GSTO1 +8 moreView in SCUBA
FibroblastsWAVE-RAC1 Actin
Cytoskeletal
BRK1, C11orf58, C4orf3, CHCHD2, DYNLRB1, MRFAP1, PPIA, RAC1 +1 moreView in SCUBA
Gamma-delta T cellsProtein Homeostasis Chaperones
Housekeeping
ATXN10, DYNLRB1, GMFG, HIGD1A, NAA10, POLR2J, PPIA, PPIB +6 more
Goblet cellsMucin O-Glycosylation
Mucus production & secretion
ACLY, ASPH, C9orf152, CKAP4, ESRP1, FABP2, IL13RA1, PLPP5 +8 moreView in SCUBA
Innate lymphoid cellsMitochondrial OxPhos
Mitochondrial & OxPhos
AKR7A2, ANXA6, AP2M1, ARL6IP4, ARPC1B, ATP5MC2, ATP5PB, BSG +21 moreView in SCUBA
MacrophagesERAD Proteasome
Housekeeping
ADRM1, EIF6, EMC6, GLRX3, GNPTG, LRPAP1, MAP2K2, MED8 +16 moreView in SCUBA
Mucosal-associated invariant T cellCyclophilin-Mediated Folding
Housekeeping
B2M, BBLN, BCL7C, C12orf75, CFL1, EDF1, EIF3L, ERH +10 more
Smooth muscle cellsMembrane Protein Turnover
Housekeeping
ATP6AP2, AXL, BSG, CAP1, CBX6, EI24, MFAP4, TCEAL9 +1 moreView in SCUBA

About the gene

SynonymsTLAP, TRAPB
Chromosome1: 156009048-156020951
Predicted locationIntracellular, Membrane
Essential geneNo
Protein classPredicted intracellular proteins, Predicted membrane proteins, Transporters

Function

TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.