MFAP4 — Microfibril associated protein 4
MFAP4 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
MFAP4's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | Microfibril ECM Fibroblast ECM production | CD302, CD81, COX7C, CYBRD1, EPHX1, NFIX, NOP53, NUCKS1 +2 more | View in SCUBA |
| Pericytes | Stromal ECM Production ECM production | ABCA8, CCL11, CFD, CTSK, DCN, FBLN1, LUM, VCAN | View in SCUBA |
| Smooth muscle cells | Membrane Protein Turnover Housekeeping | ATP6AP2, AXL, BSG, CAP1, CBX6, EI24, SSR2, TCEAL9 +1 more | View in SCUBA |
About the gene
| Chromosome | 17: 19383442-19387190 |
|---|---|
| Predicted location | Secreted |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted secreted proteins |
| Biological process | Cell adhesion |
Function
Could be involved in calcium-dependent cell adhesion or intercellular interactions. May contribute to the elastic fiber assembly and/or maintenance
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.