FANCA — FA complementation group A
FANCA belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
FANCA's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | S-phase DNA Replication Cell cycle | CHEK1, DNAJC9, HELLS, LIG1, MCM7, PCNA, RFC4, WDR76 | View in SCUBA |
About the gene
| Synonyms | FA-H, FAA, FACA, FAH, FANCH |
|---|---|
| Chromosome | 16: 89726683-89816977 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins |
| Biological process | DNA damage, DNA repair |
Function
DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.