WDR76 — WD repeat domain 76
WDR76 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
WDR76's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | Replication Licensing Cell cycle | ASF1B, CDC6, CDCA5, CDT1, CENPK, CENPU, CLSPN, DNAJC9 +5 more | View in SCUBA |
| CD8⁺ T cells | DNA Replication Fork Cell cycle | CDC6, CDT1, CHAF1A, CTNNAL1, DHFR, DUT, FEN1, LIG1 +5 more | View in SCUBA |
| Endothelial | S-phase DNA Replication Cell cycle | CHEK1, DNAJC9, FANCA, HELLS, LIG1, MCM7, PCNA, RFC4 | View in SCUBA |
| Hematopoietic progenitor cells | Replication Origin Licensing Cell cycle | BRCA1, CDC6, CLSPN, DTL, FAM111B, MCM10, ORC6, XRCC2 |
About the gene
| Synonyms | FLJ12973 |
|---|---|
| Chromosome | 15: 43826980-43868412 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Predicted intracellular proteins |
Function
Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.