SCUBA

FBXW2 — F-box and WD repeat domain containing 2

FBXW2 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

FBXW2's module in each cell type

Cell typeModuleShares the module with
NeutrophilsApoptotic Neutrophil Program
Developmental
ANO10, APAF1, ARFGEF1, ATF7IP, BLTP1, CEP350, FAR2, HIPK2 +5 more

About the gene

SynonymsFBW2, Fwd2, Md6
Chromosome9: 120751978-120793416
Predicted locationIntracellular
Essential geneNo
Protein classPredicted intracellular proteins
Biological processUbl conjugation pathway

Function

Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.