FOXF2 — Forkhead box F2
FOXF2 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
FOXF2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Smooth muscle cells | FOXF2 Mesenchymal Patterning Development | ADAMTS6, APCDD1, BDKRB2, DCHS1, FAT4, KCNH2, MFAP5, P2RY14 +2 more | View in SCUBA |
About the gene
| Synonyms | FKHL6, FREAC2 |
|---|---|
| Chromosome | 6: 1389576-1395603 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Transcription factors |
| Molecular function | Activator, DNA-binding |
| Biological process | Transcription, Transcription regulation |
Function
Probable transcription activator for a number of lung- specific genes. Mediates up-regulation of the E3 ligase IRF2BPL and drives ubiquitination and degradation of CTNNB1.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.