ADAMTS6 — ADAM metallopeptidase with thrombospondin type 1 motif 6
ADAMTS6 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ADAMTS6's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | Adhesion/Migration migration & adhesion | ADAM28, ARHGAP24, ARHGAP5, CHPT1, CLMN, CMTR2, FCMR, JAM3 +11 more | View in SCUBA |
| Endothelial | Vascular Tone Regulation Endothelial cell development | ATP1A1, ATP1B3, ATP5PF, CALD1, CAVIN3, CCDC3, CD81, HMOX2 +13 more | View in SCUBA |
| Fibroblasts | Stromal Niche Identity Developmental | CNTNAP3B, HHIP, MACROD2, MYOCD, NELL1, RALGPS2, RPE65 | View in SCUBA |
| Lymphatic endothelial | DPP4+ Progenitor State migration & adhesion | CD24, DPP4, GSTM3, ISYNA1, PIK3C2G, SBSPON, TCTN3 | View in SCUBA |
| Smooth muscle cells | FOXF2 Mesenchymal Patterning Development | APCDD1, BDKRB2, DCHS1, FAT4, FOXF2, KCNH2, MFAP5, P2RY14 +2 more | View in SCUBA |
About the gene
| Synonyms | ADAM-TS6 |
|---|---|
| Chromosome | 5: 65148738-65481920 |
| Predicted location | Secreted |
| Essential gene | No |
| Protein class | Cancer-related genes, Predicted secreted proteins |
| Molecular function | Hydrolase, Metalloprotease, Protease |
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.