BDKRB2 — Bradykinin receptor B2
BDKRB2 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
BDKRB2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | VEGF Tip Cell Signaling Endothelial cell development | ADAMTS5, CA2, CBLB, CCND1, DGKD, ESM1, GABRD, GNAI1 +7 more | View in SCUBA |
| Fibroblasts | Caveolae Mechanosensing Cytoskeletal | APLP2, ARHGAP18, CACNA1H, CAV1, CAV2, CD9, CPED1, DMD +10 more | View in SCUBA |
| Pericytes | UC Inflammatory Activation Inflammatory | CD200, CSF2RB, DUSP23, HLA-DQA1, MEOX1, NR5A2, PCDH17, RGCC +3 more | View in SCUBA |
| Smooth muscle cells | FOXF2 Mesenchymal Patterning Development | ADAMTS6, APCDD1, DCHS1, FAT4, FOXF2, KCNH2, MFAP5, P2RY14 +2 more | View in SCUBA |
About the gene
| Synonyms | BK-2 |
|---|---|
| Chromosome | 14: 96204679-96244166 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters |
| Molecular function | G-protein coupled receptor, Receptor, Transducer |
Function
Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.