MFAP5 — Microfibril associated protein 5
MFAP5 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
MFAP5's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Caveolae-mediated Transcytosis Metabolite transfer | ADIPOR2, CAV1, CAV2, CCDC85A, CD320, EEPD1, EMP2, ENAH +19 more | View in SCUBA |
| Fibroblasts | TGF-beta Fibroblast Niche ECM production | APCDD1, BAG2, C12orf75, CD55, CES1, CGREF1, COL11A1, CRYAB +8 more | View in SCUBA |
| Smooth muscle cells | FOXF2 Mesenchymal Patterning Development | ADAMTS6, APCDD1, BDKRB2, DCHS1, FAT4, FOXF2, KCNH2, P2RY14 +2 more | View in SCUBA |
About the gene
| Synonyms | MAGP2, MP25 |
|---|---|
| Chromosome | 12: 8637346-8662888 |
| Predicted location | Intracellular, Secreted |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins |
Function
May play a role in hematopoiesis. In the cardiovascular system, could regulate growth factors or participate in cell signaling in maintaining large vessel integrity (By similarity). Component of the elastin-associated microfibrils
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.