GALNT18 — Polypeptide N-acetylgalactosaminyltransferase 18
GALNT18 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
GALNT18's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Venous Endothelial Identity Endothelial cell development | ACE, ADARB1, CDC42EP1, CLSTN1, EMCN, FLT1, GPRC5B, GSN +11 more | View in SCUBA |
| Pericytes | Vascular Permeability Migration & adhesion | ABI3, FLT1, ITGA6, NQO1, PLVAP, PRKCH, TM4SF18 | View in SCUBA |
About the gene
| Synonyms | GalNAc-T18, GALNT15, GALNTL4, MGC71806 |
|---|---|
| Chromosome | 11: 11270877-11622005 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Predicted membrane proteins |
| Molecular function | Glycosyltransferase, Transferase |
Function
Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine (GalNAc) residue from UDP-GalNAc to a serine or threonine residue on the protein receptor
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.