GALNT5 — Polypeptide N-acetylgalactosaminyltransferase 5
GALNT5 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
GALNT5's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Goblet cells | Golgi-Exocytosis Machinery Mucus production & secretion | BCAS1, GOLGA2, GOLGA3, MIA3, MLPH, PLA2G10, RRBP1, SEC31A +2 more | View in SCUBA |
About the gene
| Synonyms | GalNAc-T5 |
|---|---|
| Chromosome | 2: 157257705-157318491 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Predicted intracellular proteins |
| Molecular function | Glycosyltransferase, Transferase |
Function
Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward EA2 peptide substrate, but has a weak activity toward Muc2 or Muc1b substrates (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.