SCUBA

RRBP1 — Ribosome binding protein 1

RRBP1 belongs to a gene co-expression module in 10 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

RRBP1's module in each cell type

Cell typeModuleShares the module with
EndothelialInflammatory Endothelial Activation
Inflammation
ANXA6, CNIH1, COTL1, DEGS1, DHRS7, F2R, FKBP10, FSTL1 +8 moreView in SCUBA
EnterocytesEpithelial NF-kB response
Inflammation
ATP10B, CASP1, CCL28, E2F3, FAM135A, GSKIP, INPP4B, LYN +4 moreView in SCUBA
FibroblastsWNT4+ Stromal Fibroblast
Developmental
CARD16, CASP1, FBLIM1, FHL2, GRK5, IQGAP2, OTULINL, PIEZO2 +7 moreView in SCUBA
Goblet cellsGolgi-Exocytosis Machinery
Mucus production & secretion
BCAS1, GALNT5, GOLGA2, GOLGA3, MIA3, MLPH, PLA2G10, SEC31A +2 moreView in SCUBA
Hematopoietic progenitor cellsMast Cell Progenitor
Granulocyte development
CD84, CPA3, FRY, GATA2, HPGDS, IKZF2, NLK, REXO5 +2 more
Innate lymphoid cellsNK Cytotoxic Regulation
Cytotoxicity
ARHGAP30, BIN2, CAPN12, CHD9, CLK1, CTSC, CYB5B, DDX27 +29 moreView in SCUBA
MacrophagesAntiviral ISG Response
Antiviral
ADAR, APOL6, ARID5A, CLEC7A, DDX60, DTX3L, EIF2AK2, ERICH1 +29 moreView in SCUBA
Natural Killer cellsNK Cell Activation
activation
AHNAK, AKT3, ANXA1, C16orf54, C1orf162, CD226, CD300A, ITGAX +2 moreView in SCUBA
PericytesInflammatory ECM Remodeling
ECM remodeling
CASP4, CHSY1, FNDC3B, GMFG, ITPRIPL2, LAMB1, MARCKSL1, NECTIN2 +5 moreView in SCUBA
Smooth muscle cellsCollagen-Laminin Deposition
ECM remodeling
COL5A1, COL5A2, COL6A3, LAMA4, LAMB1, NEGR1, PARVA, PCDH7 +4 moreView in SCUBA

About the gene

SynonymsES/130, hES, p180
Chromosome20: 17613678-17682295
Predicted locationIntracellular, Membrane
Essential geneNo
Protein classPlasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Biological processProtein transport, Translocation, Transport

Function

Acts as a ribosome receptor and mediates interaction between the ribosome and the endoplasmic reticulum membrane

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.