SEC31A — SEC31 homolog A, COPII coat complex component
SEC31A belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SEC31A's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | Collagen ECM Production ECM production | AEBP1, ANGPTL2, ANTXR1, CERCAM, CLTC, COL1A1, COL1A2, COL3A1 +12 more | View in SCUBA |
| Goblet cells | Golgi-Exocytosis Machinery Mucus production & secretion | BCAS1, GALNT5, GOLGA2, GOLGA3, MIA3, MLPH, PLA2G10, RRBP1 +2 more | View in SCUBA |
| Macrophages | ER-Golgi Trafficking Vesicular traficking | ADD1, AFTPH, AZIN1, COPA, DYNC1H1, HNRNPC, JOSD1, LCP2 +23 more | View in SCUBA |
| Mucosal-associated invariant T cell | Cytoskeletal Remodeling Migration migration & adhesion | ADAM8, BIN2, C11orf21, CAPN1, CAPN2, CD52, CDC25B, CNN2 +14 more | |
| Pericytes | Basement Membrane Assembly ECM production | F2R, FARP1, ITGB1, JAK1, LAMA4, LAMC1, LIMS1, NID1 +1 more | View in SCUBA |
About the gene
| Synonyms | ABP125, ABP130, KIAA0905, SEC31L1 |
|---|---|
| Chromosome | 4: 82818509-82901166 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters |
| Biological process | ER-Golgi transport, Protein transport, Transport |
Function
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.