GFRA3 — GDNF family receptor alpha 3
GFRA3 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
GFRA3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Glial cells | Neural Migration Scaffold Cytoskeletal | ABLIM1, ALCAM, ANK3, CAB39L, GAS2L3, IQGAP2, NRXN1, RELN +1 more | View in SCUBA |
About the gene
| Synonyms | GFRa-3 |
|---|---|
| Chromosome | 5: 138252380-138274621 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Predicted membrane proteins |
| Molecular function | Receptor |
Function
Receptor for artemin (ARTN), a growth factor that supports the survival of sensory and sympathetic peripheral neurons. ARTN-binding leads to autophosphorylation and activation of the RET receptor.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.