IRF6 — Interferon regulatory factor 6
IRF6 belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
IRF6's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | GPCR Peptide Signaling Secretion | ABHD11, AKIRIN1, AVPI1, BAG1, DNAJA1, DNAJA2, EDN1, FBXO33 +31 more | View in SCUBA |
About the gene
| Synonyms | LPS, OFC6, VWS, VWS1 |
|---|---|
| Chromosome | 1: 209785617-209806175 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors |
| Molecular function | DNA-binding |
| Biological process | Differentiation, Transcription, Transcription regulation |
Function
Probable DNA-binding transcriptional activator. Key determinant of the keratinocyte proliferation-differentiation switch involved in appropriate epidermal development (By similarity). Plays a role in regulating mammary epithelial cell proliferation (By similarity). May regulate WDR65 transcription (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.