DNAJA2 — DnaJ heat shock protein family (Hsp40) member A2
DNAJA2 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
DNAJA2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | T-cell activation TCR/AP1/NFKb pathway | C16orf87, CAMK1, CBLB, CD4, CD7, CDK6, CIAO1, COPB2 +7 more | View in SCUBA |
| Innate lymphoid cells | RNA Chromatin Regulation RNA processing & translation | ACADM, AURKAIP1, BUD23, CBX3, CMC2, COPB1, DYNC1LI1, G3BP1 +19 more | View in SCUBA |
| Macrophages | Protein Biogenesis Housekeeping | ATP6V0D1, B3GAT3, BUD23, C11orf58, CHD4, CNPY2, DAZAP1, DDX46 +23 more | View in SCUBA |
About the gene
| Synonyms | CPR3, DNAJ, DNJ3, HIRIP4 |
|---|---|
| Chromosome | 16: 46955362-46973674 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | Chaperone |
Function
Co-chaperone of Hsc70. Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.