SCUBA

MPDZ — Multiple PDZ domain crumbs cell polarity complex component

MPDZ belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

MPDZ's module in each cell type

Cell typeModuleShares the module with
Lymphatic endothelialChromatin Remodeling
DNA/chromatin regulation
BAZ2B, CHD9, ITFG1, JMJD1C, MICAL3, PACSIN2, PHKB, PLXDC2 +4 moreView in SCUBA

About the gene

SynonymsMUPP1
Chromosome9: 13105706-13279692
Predicted locationIntracellular
Essential geneNo
Protein classDisease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins
Biological processHost-virus interaction

Function

Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses. Promotes clustering of HT2RC at the cell surface (By similarity).

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.