ITFG1 — Integrin alpha FG-GAP repeat containing 1
ITFG1 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ITFG1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Autophagy & Trafficking Housekeeping | ABCD2, ASCC3, ATG7, ATP9B, BTBD9, IKBKE, KLF12, PALM2AKAP2 +11 more | |
| Lymphatic endothelial | Chromatin Remodeling DNA/chromatin regulation | BAZ2B, CHD9, JMJD1C, MICAL3, MPDZ, PACSIN2, PHKB, PLXDC2 +4 more | View in SCUBA |
| Macrophages | MITF Lysosomal Program Lysosomal & pahgocytosis | ABHD3, ANKRD44, ARSB, C2CD5, CERS6, CHST11, CNST, DCTN4 +25 more | View in SCUBA |
About the gene
| Synonyms | CDA08, LNKN-1, TIP |
|---|---|
| Chromosome | 16: 47154387-47464149 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins |
Function
Modulator of T-cell function. Has a protective effect in graft versus host disease model (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.