MTHFD1L — Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
MTHFD1L belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
MTHFD1L's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Monocytes | Myeloid Epigenetic Regulation Developmental | CYRIA, GPRC5A, H2AC25, MN1, PCGF5, PDE2A, PPP1R14B, RAPH1 +1 more | View in SCUBA |
About the gene
| Synonyms | DKFZP586G1517, FLJ21145, FTHFSDC1 |
|---|---|
| Chromosome | 6: 150865679-151101887 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins |
| Molecular function | Ligase |
| Biological process | One-carbon metabolism |
Function
May provide the missing metabolic reaction required to link the mitochondria and the cytoplasm in the mammalian model of one-carbon folate metabolism complementing thus the enzymatic activities of MTHFD2
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.