RAPH1 — Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
RAPH1 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
RAPH1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Lymphatic endothelial | ECM-driven Migration migration & adhesion | FMNL2, GLIS3, LAMC1, MAML2, PCSK6, SGIP1, ST3GAL6, STK32B +2 more | View in SCUBA |
| Macrophages | Macrophage Migration Migration & adhesion | CEMIP2, CPM, EPB41L2, EPS8, GBE1, ITGA9, KCNQ1, MAN1A1 +12 more | View in SCUBA |
| Monocytes | Myeloid Epigenetic Regulation Developmental | CYRIA, GPRC5A, H2AC25, MN1, MTHFD1L, PCGF5, PDE2A, PPP1R14B +1 more | View in SCUBA |
About the gene
| Synonyms | ALS2CR18, ALS2CR9, KIAA1681 |
|---|---|
| Chromosome | 2: 203394345-203535335 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
Mediator of localized membrane signals. Implicated in the regulation of lamellipodial dynamics. Negatively regulates cell adhesion
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.