PLP1 — Proteolipid protein 1
PLP1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PLP1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Glial cells | Glial Myelination Identity Myelination | AP1S2, CALM2, CD81, CD9, COMT, GPM6B, GSN, IGFBP7 +6 more | View in SCUBA |
About the gene
| Synonyms | GPM6C, PLP, SPG2 |
|---|---|
| Chromosome | X: 103773718-103792619 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters |
Function
This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.