GPM6B — Glycoprotein M6B
GPM6B belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
GPM6B's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | Chemokine-secreting Fibroblasts Inflammatory | CA12, CCBE1, CHI3L2, CPXM2, CXCL13, CXCL5, GAS1, IGFBP2 +10 more | View in SCUBA |
| Glial cells | Glial Myelination Identity Myelination | AP1S2, CALM2, CD81, CD9, COMT, GSN, IGFBP7, LGALS1 +6 more | View in SCUBA |
About the gene
| Synonyms | M6B, MGC17150, MGC54284 |
|---|---|
| Chromosome | X: 13770939-13938638 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Predicted membrane proteins |
| Molecular function | Developmental protein |
| Biological process | Differentiation, Neurogenesis, Osteogenesis, Protein transport, Transport |
Function
May be involved in neural development. Involved in regulation of osteoblast function and bone formation. Involved in matrix vesicle release by osteoblasts; this function seems to involve maintenance of the actin cytoskeleton. May be involved in cellular trafficking of SERT and thereby in regulation of serotonin uptake
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.