PPA2 — Inorganic pyrophosphatase 2
PPA2 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PPA2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Macrophages | Ribosome Biogenesis Cell cycle | ACAT1, ANAPC5, CFDP1, IKBIP, MGME1, MGMT, NAA15, NAA25 +8 more | View in SCUBA |
About the gene
| Synonyms | FLJ20459 |
|---|---|
| Chromosome | 4: 105369077-105474067 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins |
| Molecular function | Hydrolase |
Function
Hydrolyzes inorganic pyrophosphate. This activity is essential for correct regulation of mitochondrial membrane potential, and mitochondrial organization and function.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.