FUCA2 — Alpha-L-fucosidase 2
FUCA2 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
FUCA2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Innate lymphoid cells | ILC-1 identity Differentiation | ABRACL, BLOC1S1, C19orf53, CD52, DAD1, GMFG, HMGN3, ISCU +20 more | View in SCUBA |
| Macrophages | ER Stress UPR Stress | ANKRD9, APEH, ARMCX6, BET1L, CALR, CCDC107, COPS2, DNAJB11 +20 more | View in SCUBA |
About the gene
| Synonyms | dJ20N2.5, MGC1314 |
|---|---|
| Chromosome | 6: 143494812-143511720 |
| Predicted location | Intracellular, Secreted |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins |
| Molecular function | Glycosidase, Hydrolase |
Function
Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.