PPRC1 — PPARG related coactivator 1
PPRC1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PPRC1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Metabolic-Translational Coupling RNA processing & translation | APOL6, ARCN1, ARGLU1, DCAF12, DDX23, EIF2S1, EIF4G1, FHOD1 +20 more |
About the gene
| Synonyms | KIAA0595, MGC74642, PRC |
|---|---|
| Chromosome | 10: 102132994-102150333 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Predicted intracellular proteins |
| Molecular function | Activator, RNA-binding |
| Biological process | Transcription, Transcription regulation |
Function
Acts as a coactivator during transcriptional activation of nuclear genes related to mitochondrial biogenesis and cell growth. Involved in the transcription coactivation of CREB and NRF1 target genes
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.