RAB3IL1 — RAB3A interacting protein like 1
RAB3IL1 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
RAB3IL1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Macrophages | Resident Mac Identity Tissue homeostasis | ACVRL1, CCND1, CD200R1, CFD, CR1, CTSF, EMB, EPHX1 +16 more | View in SCUBA |
| Monocytes | Tissue-Resident Macrophage Tissue adaptation | DAB2, ETV5, FOLR2, FRMD4A, GPNMB, ITGB5, LGMN, LILRB5 +7 more | View in SCUBA |
About the gene
| Synonyms | GRAB |
|---|---|
| Chromosome | 11: 61897301-61920269 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | Guanine-nucleotide releasing factor |
| Biological process | Protein transport, Transport |
Function
Guanine nucleotide exchange factor (GEF) which may activate RAB3A, a GTPase that regulates synaptic vesicle exocytosis. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. May also activate RAB8A and RAB8B
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.