REEP6 — Receptor accessory protein 6
REEP6 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
REEP6's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | Gluconeogenesis/fructose metabolism Nutrient metabolism | AADAC, ADIRF, ENTPD5, FBP1, HEBP1, KHK, PCK2, PEPD +2 more | View in SCUBA |
About the gene
| Synonyms | C19orf32, DP1L1, FLJ25383, Yip2f |
|---|---|
| Chromosome | 19: 1491166-1497927 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted membrane proteins |
Function
Required for correct function and survival of retinal photoreceptors. Required for retinal development (By similarity). In rod photoreceptors, facilitates stability and/or trafficking of guanylate cyclases and is required to maintain endoplasmic reticulum and mitochondrial homeostasis (By similarity). May play a role in clathrin-coated intracellular vesicle trafficking of proteins from the endoplasmic reticulum to the retinal rod plasma membrane (By similarity).
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.